Patent · US Expired

2-(2-cyclopropylpyrrolidin-4-ylthio)carbapenhem derivatives

US5112818A · kind A · utility

5Cited by
5References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 28, 1990
Grant dateMay 12, 1992
Priority date
Expiry dateDec 28, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D477/20
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom or a methyl group, each of R.sup.2 and R.sup.3 which may be the same or different, is a hydrogen atom or a lower alkyl group, or R.sup.2 and R.sup.3 form together with the adjacent nitrogen atom a heterocyclic group selected from the group consisting of an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a piperazinyl group and a morpholino group, A is a carbonyl group or a single bond, and n is an integer of from 0 to 3; or a pharmaceutically acceptable salt or ester thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.