Radiolabeled proteins for diagnostic or therapeutic use
US5112953A · kind A · utility
25Cited by
9References
40Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 1989 |
| Grant date | May 12, 1992 |
| Priority date | — |
| Expiry date | Dec 29, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Chelating compounds of specified structure are useful for radiolabeling targeting molecules such as antibodies. Cleavable linkers connect the radionuclide metal chelates to the antibodies. The radiolabeled antibodies have improved biodistribution properties, including reduced localization within the intestines and kidneys.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.