Patent · US Expired

Superfusion apparatus

US5114681A · kind A · utility

31Cited by
7References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 9, 1990
Grant dateMay 19, 1992
Priority date
Expiry dateMar 9, 2010

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2035/102
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A superfusion apparatus for the controlled reaction of a sample within a test chamber through controlled exposure to a series of reagents in a set test sequence is provided for electrical or chemical stimulation to determine if a receptor binding compound is an agonist or antagonist. The superfusion apparatus provides a mass production but meticulously controlled sample environment for controlling temperature, quantity and arrangement of reagents and wash fluids to provide a high reproducability of results which may be compuer assisted. The device has a fully automated mode or a manually operated mode. The fully automated mode allows for the storage and execution of a number of different tests to be performed on the samples due to the provision of desired sequences of test parameters.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.