Patent · US Expired

Preparation of T-cell and T-cell membrane for use in prevention and treatment of autoimmune diseases

US5114721A · kind A · utility

62Cited by
4References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 15, 1989
Grant dateMay 19, 1992
Priority date
Expiry dateMar 15, 2009

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Pharmaceutical preparations are provided for preventing or treating autoimmune diseases in which the active principle is activated T-lymphocyte cells, specific for the autoimmune disease to be treated, which cells have been treated by incubation with a photoactivatable psoralen cross-linking agent, such as 8-methoxypsoralen, and then photoactivated. The active principle may also be the membrane fraction of such cells. Such preparations may be formulated into pharmaceutical compositions and administered to prevent or treat autoimmune disesases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.