Patent · US Expired

Drug combinations containing AZT

US5116823A · kind A · utility

9Cited by
3References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 1990
Grant dateMay 26, 1992
Priority date
Expiry dateFeb 27, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/505
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Combinations of 3'-azido-3'-deoxythymidine (AZT) with 5-fluorouracil (FUra) or its precursor 5-fluoro-2'-deoxyuridine (FUDR) or methoxtrexate (MTX) exhibit increased cytotoxicity and increased therapeutic index in treatment of carcinomas.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.