Chemical compounds
US5116842A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 17, 1990 |
| Grant date | May 26, 1992 |
| Priority date | — |
| Expiry date | May 17, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds are disclosed of formula (I) ##STR1## wherein R.sub.1 represents --COR.sub.4, --CO.sub.2 R.sub.4, --COCO.sub.2 R.sub.4 or --CONR.sub.4 R.sub.5 (where R.sub.4 and R.sub.5 may be the same or different and represent a hydrogen atom or a C.sub.1-3 alkyl group); PA1 R.sub.2 represents a hydrogen atom or a hydroxy or oxo group, with the proviso that when R.sub.1 is --COR.sub.4, --CO.sub.2 R.sub.4 or --COCO.sub.2 R.sub.4, R.sub.2 is not a hydrogen atom; PA1 R.sub.3 represents a hydrogen atom or a hydroxy group; PA1 X represents a direct bond, --CH.sub.2 -- or --CH.sub.2 O--; PA1 Ar represents a substituted phenyl moiety; and physiologically acceptable salts thereof. The compounds are indicated as useful in the treatment of pain. Processes for their preparation and pharmaceutical compositions containing them are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.