Method for determining fibrin fiber size from a single gel optical density measurement
US5118182A · kind A · utility
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10Claims
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Key dates
| Filing date | Oct 5, 1990 |
| Grant date | Jun 2, 1992 |
| Priority date | — |
| Expiry date | Oct 5, 2010 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/974
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Experiments have been conducted which demonstrate that gel optical density is a linear function of the fibrin fiber mass/length ratio (.mu.) and that the slope of the linear function is dependent on the concentration of fibrinogen in the sample. Once the linear function is known, knowledge of a gel optical density at one wavelength is adequate to determine .mu.. Such measurements allow quantitative monitoring of fibrin structure, and are clinically relevant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.