Carrier fleece for use as a reagent carrier from which reagents can be dissolved in immunological analysis

US5118609A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Manfred Baier · Starnberg, DE
• Helmut Jering · Tutzing, DE
• Rolf Lerch · Ilvesheim, DE
• Dieter Mangold · Frankenthal (Pfalz), DE
• Ellen Mossner · Tutzing, DE
• Gunter Pappert · Tutzing, DE
• Siegfried Notzel · Wilhelmsfeld, DE

Key dates

• Filing date: Jan 31, 1991
• Grant date: Jun 2, 1992
• Expiry date: Jan 31, 2011

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/815
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A carrier fleece is prepared for use as reagent carrier from which reagents can be dissolved in as assay such as immunological analysis. The carrier fleece contains from 5 to 60% by weight of cellulose-containing fibers, from 40 to 95% by weight of polyester or polyamide polymer fibers or a combination thereof and from 5 to 30% by weight of the fibers of an organic binding agent which has a hydroxyl or an ester group or a combination thereof. In an immunological analysis, the carrier fleece is impregnated with an immunologically active agent such as a beta-galactosidase conjugate and then introduced into a solution of a sample containing an immunologically active substance to be analyzed. The immunologically active agent is eluted into the sample solution and the presence of the immunologically active substance in the sample is determined.