Peptide and gene coding for same
US5118615A · kind A · utility
5Cited by
4References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 9, 1987 |
| Grant date | Jun 2, 1992 |
| Priority date | — |
| Expiry date | Mar 9, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a DNA fragment comprising a base sequence coding for a peptide occurring in human atrium cordis and having diuretic action or a precursor of the peptide, plasmids containing the DNA fragment, microorganisms transformed with the plasmid, and a process for production of the peptide using the transformant. Also disclosed is a new peptide consisting of 126 amino acids occurring in human atrium cordis and a precursor thereof. The peptide has notable diuretic action and hypotensive or antihypertensive actions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.