SAF polypeptide, gene coding therefor, SAF promoter and expression methods for expressing foreign DNA sequences in streptomyces
US5118617A · kind A · utility
5Cited by
1References
30Claims
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Key dates
| Filing date | Sep 22, 1989 |
| Grant date | Jun 2, 1992 |
| Priority date | — |
| Expiry date | Sep 22, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/886
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The cloning and characterization of a newly isolated gene, referred to as saf (secondary metabolism activation factor) is disclosed. This gene encodes a new amino acid polypeptide, referred to as the SAF polypeptide, which directly or indirectly modulates the expression of extracellular enzymes in Streptomyces. DNA units or fragments which encode the SAF polypeptides are also disclosed, as are vectors containing said DNA, host organisms transformed with such vectors, and processes for preparing extracellular enzymes or heterologous polypeptides by culturing such host organisms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.