Process for preparing aldehydes from base sensitive amines
US5118810A · kind A · utility
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2Claims
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Key dates
| Filing date | Jul 6, 1990 |
| Grant date | Jun 2, 1992 |
| Priority date | — |
| Expiry date | Jul 6, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is disclosed a process for preparing aldehydes from base sensitive amines. The process can be employed to obtain carboxylic acid methyl esters. In particular, thiazolidine carboxylic methyl ester can be produced which is useful as an intermediate in the preparation of bicyclic lactam compounds. These bicyclic lactam compounds are potent angiotesin converting enzyme (ACE) inhibitors useful in the treatment of hypertension, congestive heart failure, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.