Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules

US5118937A · kind A · utility

Assignee

• Finnigan MAT GmbH · DE

Inventors

• Franz Hillenkamp · Münster, DE
• Michael Karas · Hattersheim, DE
• Ulrich Giessmann · Bremen, DE

Key dates

• Filing date: Aug 21, 1990
• Grant date: Jun 2, 1992
• Expiry date: Aug 21, 2010

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2001/045
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to a process for the laser desorption of analyte molecular ions, especially of biomolecules, from a specimen. The object of the invention is to improve a process of this type in such a way that intact desorption of biomolecules, preferably of large molecular mass, is also possible with a laser. This is achieved by using laser light of a wavelength of about 300 nm or greater than 300 nm and using a matrix which is able to absorb in the selected wavelength range.