Method and apparatus for non-invasive monitoring of blood glucose
US5119819A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 2, 1990 |
| Grant date | Jun 9, 1992 |
| Priority date | — |
| Expiry date | May 2, 2010 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2291/02881
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A new and improved method and apparatus are provided for non-invasive monitoring of changes in blood glucose concentration in a tissue specimen and particularly in an individual. The method uses acoustic velocity measurements for monitoring the effect of glucose concentration upon the density and adiabatic compressibility of the serum. In a preferred embodiment, the acoustic velocity measurements are made through the earlobe of a subject by means of an acoustic probe or monitor which includes a transducer for transmitting and receiving ultrasonic energy pulses to and from the blood flowing in the subject's earlobe and a reflector for facilitating reflection of the acoustic pulses from the blood. The probe is designed in such a way that when properly affixed to an ear, the transducer is positioned flush against the anterior portion of an earlobe while the reflector is positioned flush against the interior portion of the earlobe. A microthermocouple is provided on the probe for monitoring the internal temperature of the blood being sampled. An electrical system, essentially comprising a frequency generator, a time intervalometer and an oscilloscope, is linked to the glucose monitorin…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.