Bicyclic rapamycins
US5120725A · kind A · utility
106Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 29, 1991 |
| Grant date | Jun 9, 1992 |
| Priority date | — |
| Expiry date | May 29, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A bicyclic derivative of rapamycin of general formula (1) ##STR1## wherein ##STR2## n=2 to 10, m=2 to 10 and PA0 n=m or n.noteq.m PA0 or a pharmaceutically acceptable salt thereof, which is by virtue of its immunosuppressive activity is useful in treating transplantation rejection host vs. graft disease, autoimmune diseases, and diseases of inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.