4-amino-4-ene-steroids and their use as 5.alpha.-reductase inhibitors
US5120840A · kind A · utility
8Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 2, 1991 |
| Grant date | Jun 9, 1992 |
| Priority date | — |
| Expiry date | Jul 2, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/0027
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to 4-amino-.DELTA..sup.4 -steroids which are useful as inhibitors of 5.alpha.-reductase. The compounds are prepared by the reaction of an appropriate 4-azido steroid with triphenylphosphine in an aqueous inert solvent with heating. The present application is a continuation-in-part of application Ser. No. 561,041, filed Aug. 1, 1990 and application Ser. No. 671,555, filed Mar. 19, 1991.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.