Pharmaceutically active amines

US5120843A · kind A · utility

Assignee

• The Upjohn Co. · US

Inventors

• John M. McCall · Kalamazoo, US
• Donald E. Ayer · Kalamazoo, US
• E. Jon Jacobsen · Plainwell, US
• Frederick J. VanDoornik · Hamilton, US
• John R. Palmer · Fishers, US

Key dates

• Filing date: Oct 23, 1989
• Grant date: Jun 9, 1992
• Expiry date: Oct 23, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The aromatic amines (I), alkyl amines (II), bicyclic amines (III). ##STR1## cycloalkyl amines (IV), aromatic bicyclic amines (V), hydroquinone amines (VI), quinone amines (VII), amino-ethers (VIII) and bicyclic amino ethers (IX) are useful as pharmaceutical agents for treating a number of conditions including spinal trauma, mild and/or moderate to severe head injury, etc. Also disclosed is a method of treatment using the 3,4-dihydrobenzopyrans (XI).