Polypeptides useful as blockers of calcium channels
US5122596A · kind A · utility
12Cited by
1References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 29, 1989 |
| Grant date | Jun 16, 1992 |
| Priority date | — |
| Expiry date | Sep 29, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/858
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a polypeptide found to be present in the venom of the Agelenopsis aperta spider and to polypeptides having substantially the same amino acid sequence and substantially the same activity as said polypeptide. The polypeptides of this invention and the salts thereof block calcium channels in cells of various organisms and are useful in blocking said calcium channels in cells, per se; in the treatment of calcium channel mediated diseases and conditions; and in the control of invertebrate pests. This invention also relates to compositions comprising said polypeptides and salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.