Anti-thrombotic heterocyclic amido prostaglandin analogs
US5126370A · kind A · utility
7Cited by
8References
24Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 24, 1990 |
| Grant date | Jun 30, 1992 |
| Priority date | — |
| Expiry date | Dec 24, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Prostaglandin analogs useful in treating thrombotic and vasospastic disease having the structural formula ##STR1## wherein: m is 1, 2 or 3: PA0 n is 1, 2 or 3, except that n is O when Y is vinylene; PA0 p is 1, 2 or 3; PA0 R is CO.sub.2 R', CH.sub.2 OH, CONHSO.sub.2 R.sup.3, CONHR.sup.4, or --CH.sub.2 -5-tetrazolyl; PA0 R' is hydrogen, alkyl, or alkali metal; PA0 Y is --O--, a single bond or vinylene, except that Y cannot be --O-- when n is 0; PA0 and the remaining symbols are as defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.