Process for the preparation of 1,4-dihydro-pyridine derivatives
US5126457A · kind A · utility
1Cited by
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16Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 8, 1989 |
| Grant date | Jun 30, 1992 |
| Priority date | — |
| Expiry date | Mar 8, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C251/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention is directed to processes for the preparation of dimethyl-1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dicarbox ylate by reacting 1-methoxy-1-(2'-nitrophenyl)-N-(2'-nitrophenyl)methylene methanamie or 1-(2'-nitrophenyl)-N,N'-bis-(2'-nitrophenyl) methylene methanediamine with methyl acetoacetate in the presence of an amine compound or by reacting the monomeric or trimeric from of 2-nitrobenzaldimine with methyl acetoacetate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.