Use of 9-anthrylalkyl compounds as derivatization reagents for separation and detection purposes

US5128120A · kind A · utility

Assignee

• Eka Nobel AB · SE

Inventors

• Hans Becker · Mölndal, SE
• Stefan Einarsson · Göteborg, SE
• Andrzej Grzegorczyk · Mölndal, SE
• Bjorn Josefsson · Göteborg, SE
• Stig S. Lagerkvist · Göteborg, SE
• Per Moller · Kungsbacka, SE
• Domingo Sanchez · Floda, SE
• Johan H. Sorensen · Göteborg, SE

Key dates

• Filing date: Feb 5, 1991
• Grant date: Jul 7, 1992
• Expiry date: Feb 5, 2011

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/204998
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New 9-anthrylalkyl compounds having the general formula ##STR1## wherein R is hydrogen or an alkyl group, whereby, however, not more than one of the groups R is an alkyl group; R.sub.1 is hydrogen, lower alkyl, halogen or nitro; n is an integer of from 1 to 7, whereby, however, the total number of carbon atoms in the group --CHR--(CHR).sub.n -- does not exceed 8; and X is halogen, an azide group or a succinimidyl group. The new compounds are prepared from 9-anthrylalcohols which are reacted with a compound X--CO--X wherein X is a halogen, and then optionally with compounds giving azide or succinimidyl group. The compounds are used as derivatization reagents for separation and detection purposes. Intermediates for preparation of the above defined 9-anthrylalkyl compounds wherein one R is an alkyl group are 9-anthrylalcohols with the group --CHR--(CHR).sub.n --OH, wherein one R is an alkyl group.