Imidazo [1,2-c] quinazoline compounds
US5128338A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 8, 1991 |
| Grant date | Jul 7, 1992 |
| Priority date | — |
| Expiry date | Mar 8, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New imidazo [1,2-c] quinazoline compounds useful as coronary smooth muscle relaxants and corresponding to the formula: ##STR1## in which: Y is oxygen or sulfur; PA0 R.sub.1 is (C.sub.1 -C.sub.6) alkyl optionally substituted by a phenyl itself optionally substituted, a (C.sub.3 -C.sub.6) cycloalkyl, optionally substituted phenyl, furyl, thienyl or acyl; PA0 R.sub.2 is hydrogen, a halogen or a (C.sub.1 -C.sub.6) alkyl optionally substituted by amino or dialkylamino; PA0 R.sub.3 is hydrogen, (C.sub.1 -C.sub.6) alkyl optionally substituted by an aryl, or R--CO--(CH.sub.2).sub.n -- [n being 1, 2 or 3, and R being (C.sub.1 -C.sub.6) alkoxy, amino, (alkyl or dialkyl)amino, morpholino or methylpiperazinyl]; and PA0 X is hydrogen or a halogen. These compounds and their physiologically tolerated salts can be used in medical treatment of coronary smooth-muscle dysfunctions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.