Imidazoline derivatives for systemic combating of ectoparasites in host animals

US5128361A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Herbert Stark · Kelkheim, DE
• Gerhard Salbeck · Hofheim, DE
• Werner Bonin · Kelkheim, DE

Key dates

• Filing date: Dec 18, 1989
• Grant date: Jul 7, 1992
• Expiry date: Dec 18, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/24
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to agents for systemic combating of ectoperasites in host animals, containing a compound of the formul I ##STR1## in which R.sup.1 denotes hydrogen, (C.sub.1 -C.sub.5)-alkyl, (C.sub.1 -C.sub.3)-halogenoalkyl or halogen; R.sup.2 and R.sup.3 independently of one another denote (c.sub.1 -C.sub.5)-alkyl, (C.sub.2 -C.sub.5)-alkenyl, (C.sub.2 -C.sub.5)-alkynyl, (C.sub.3 -C.sub.7)-cycloalkyl, (C.sub.3 -C.sub.7)-cycloalkenyl, (C.sub.1 -C.sub.3)-halogenoalkyl, halogen, cyano, nitro, (C.sub.1 -C.sub.5)-alkoxy, (C.sub.1 -C.sub.3)-alkoxy-C.sub.1 -C.sub.3)-alkyl, (C.sub.1 -C.sub.3)-halogenoalkoxy or (C.sub.1 -C.sub.3)-alkylthio, or R.sup.2 and R.sup.3 together form a polymethylene chain having 2 to 5 carbon atoms: PA0 R.sup.4 denotes hydrogen, (c.sub.1 -C.sub.10)-alkyl, (C.sub.2 -C.sub.5)-alkenyl or (C.sub.3 -C.sub.7)-cycloalkyl; PA0 R.sup.5 denotes hydrogen, (C.sub.1 -C.sub.10)-alkyl, (C.sub.3 -C.sub.5)-alkenyl, C.sub.3 -C.sub.5)-alkynyl, (C.sub.3 -C.sub.7)- cycloalkyl, (C.sub.3 -C.sub.7)-cycloalkenyl, (C.sub.1 -C.sub.3)-halogenoalkyl or (C.sub.1 -C.sub.3)-alkoxy-(C hd 1-C.sub.3)-alkyl; PA0 X denotes oxygen, sulfur or an --NR.sup.6 --group; and PA0 R.sup.6 denotes…