Methods and materials for the preparation of metal labelled antibody solutions
US5130118A · kind A · utility
19Cited by
3References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1987 |
| Grant date | Jul 14, 1992 |
| Priority date | — |
| Expiry date | Nov 6, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25125
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a metal ion scavenging procedure and antibody compositions for radioimmunoscintigraphy and cytotoxic radioimmunotherapy having chelator concentrations of greater than about 10.sup.-4 M which are optimized with respect to their metal binding capacity such that highly efficient labelling of the antibody is achieved in a simple one step procedure using readily available sources of radiometal ions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.