Polymer-drug conjugate and a method of producing it
US5130126A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 28, 1991 |
| Grant date | Jul 14, 1992 |
| Priority date | — |
| Expiry date | Mar 28, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a polymer-combined drug having directional characteristics to digestive organs, wherein it comprises a medicine combined with a polymer which has an alkyleneoxy group as a repeating unit. The polymer-combined drug is produced by reacting a polyoxyalkylene glycol having one or more terminal functional groups and a medicine, if necessary in a solvent, and if necessary in the presence of a catalyst. It is able to administer the drug orally or by intravenous injection so as to maintain the concentration in blood stably for a long time, and to absorb or take in digestive organs such as the stomach and intestines directly.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.