Ocular implants and methods for their manufacture

US5130160A · kind A · utility

Assignee

• University of Florida Foundation, Incorporated · US

Inventors

• Eugene P. Goldberg · Gainesville, US
• James W. Burns · Watertown, US
• G. Sudesh Kunar · Jamkhed, IN
• David C. Osborn · Manchester, US
• Jeffrey A. Larson · Monrovia, US
• John W. Sheets, Jr. · Fort Worth, US
• Ali Yahiaoui · Roswell, US
• Richard D. Robinson · Ithaca, US

Key dates

• Filing date: Oct 5, 1990
• Grant date: Jul 14, 1992
• Expiry date: Oct 5, 2010

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S623/901
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method for modifying an ocular implant polymer surface by the gamma-irradiation or electron beam irradiation induced polymerization thereon of N-vinylpyrrolidone, 2-hydroxyethylmethacrylate or a mixture thereof while maintaining the following conditions: PA1 (a) monomer concentration in the range of from about 0.1% to about 50%, by weight; PA1 (b) total gamma dose in the range of from about 0.001 to less than about 0.50 Mrad; and PA1 (c) gamma dose rate in the range of from about 10 to about 2500 rads/minute or electron beam irradiation dose rate in the range of from about 10 to about 10.sup.8 rads/minute.