Patent · US Expired

Superoxide dismutase

US5130245A · kind A · utility

22Cited by
2References
16Claims
0Family size

Inventors

Key dates

Filing dateAug 27, 1990
Grant dateJul 14, 1992
Priority date
Expiry dateAug 27, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K16/40
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A superoxide dismutase originally found in extracellular body fluids and therefore termed extracellular superoxide dismutase (EC-SOD) is prepared by growing a cell line, preferably of mammalian origin, producing EC-SOD and recovering the EC-SOD secreted from the cells or by inserting a DNA sequence encoding EC-SOD into a suitable vector, introducing the recombinant vector into a host cell, growing the cell and recovering the EC-SOD produced. EC-SOD may be used for the prophylaxis or treatment of diseases or disorders associated with the presence or formation of superoxide radicals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.