Patent · US Expired

Boronated nucleoside, nucleotide and oligonucleotide compounds, compositions and methods for using same

US5130302A · kind A · utility

506Cited by
0References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 20, 1989
Grant dateJul 14, 1992
Priority date
Expiry dateDec 20, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H23/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A novel class of pharmaceutically active boronated nucleosides are provided. The nucleosides are boronated at a ring nitrogen of the purine or pyrimidine or analogues thereof. Also provided are phosphate esters of these nucleosides and oligomers thereof. Methods of making and using the boronated nucleosides are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.