Cyclophosphamide - sodium bicarbonate lyophilizates
US5130305A · kind A · utility
10Cited by
3References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 15, 1990 |
| Grant date | Jul 14, 1992 |
| Priority date | — |
| Expiry date | Oct 15, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stable rapidly dissoloving lyophilized and hydrated composition of cyclophosphamide and sodium bicarbonate is provided which contains an amount of water which is at least equimolar to the combined amount of cyclophosphamide and sodium bicarbonate in the composition and the weight ratio of cyclophosphamide to sodium bicarbonate is about 1:0.5 to 1:1.5; the composition is preferably prepared from a solution containing at least 1% (W/V) weight sodium bicarbonate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.