Chromogenic thiol indicators based on an isobenzothiazolone ring system
US5130433A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 2, 1990 |
| Grant date | Jul 14, 1992 |
| Priority date | — |
| Expiry date | Jul 2, 2010 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N31/22
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Newly synthesized chromogenic thiol-indicating benzoisothiazolone derivatives having the structure: ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, are useful in the detection of thiols, particularly in an aqueous system. This process comprises contacting the aqueous system with a chromogenic thiol-indicating benzoisothiazolone derivative as described herein. Chromophoric changes due to thiol-mediated reduction of the benzothiazolone derivative then occur. Such changes can be in a solution or on an indicator surface in contact or having been in contact with the aqueous system. The chromophoric changes, due to a bathochromic shift in characteristic light absorption upon reduction of the benzoisothiazolone derivative, are proportional to the amount or rate of appearance of thiols in the aqueous system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.