Fluorescent compounds for tagging nucleic acid probes
US5130446A · kind A · utility
15Cited by
4References
3Claims
0Family size
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Key dates
| Filing date | Mar 14, 1989 |
| Grant date | Jul 14, 1992 |
| Priority date | — |
| Expiry date | Mar 14, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6816
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Fluorescent linker moieties are provided which comprise a fluorescent compound such as fluorescein attached to a linker moiety such that a functional group of the linker is available for attachment to an affinity molecule such as a nucleic acid which has an N.sup.4 (substituted amino) cytosine moiety. Probes tagged with fluorescent derivatives such as fluorescein, tetramethyrhodamine or tetraethylrhodamine may be detected by fluorescence spectroscopic methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.