Isolation of stearidonic acid from fatty acid mixtures
US5130449A · kind A · utility
40Cited by
2References
20Claims
0Family size
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Key dates
| Filing date | May 9, 1990 |
| Grant date | Jul 14, 1992 |
| Priority date | — |
| Expiry date | May 9, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substantially pure stearidonic acid is isolated from a mixture of polyunsaturated fatty acids by fractionating at 25% to 35% by weight solution of fatty acids by high-performance reverse-phase liquid chromatography using a mobile phase of 75% to 95% by weight methanol and 25% to 5% by weight water. The isolated stearidonic acid is used to prepare pharmaceutical compositions which are administered to treat cardiovascular and thrombo-embolic diseases associated with platelet aggregation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.