Hydrolytically degradable hydrophilic gels and the method for preparation thereof using N,O-dimethacryloylhydroxylamine as a cross-linking agent
US5130479A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1991 |
| Grant date | Jul 14, 1992 |
| Priority date | — |
| Expiry date | Dec 10, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S524/916
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The solution pertains to hydrolytically degradable hydrophilic gels consisting of the individual chains of hydrophilic polymer interconnected with crosslinks containing the structure unit ##STR1## The method for preparation of the hydrolytically degradable gels consists in subjecting hydrophilic monomers or their mixture to the radical polymerization or copolymerization, or to copolymerization with hydrophobic monomers, in the presence of a new compound--N,O-dimethacryloylhydroxylamine--as a crosslinking agent, and, if desired, in the presence of a solvent, whereas the amount of hydrophilic monomers is 50 to 99.8 molar percent related to all monomers present.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.