HS-142-1 compounds
US5132112A · kind A · utility
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6Claims
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Key dates
| Filing date | Apr 9, 1991 |
| Grant date | Jul 21, 1992 |
| Priority date | — |
| Expiry date | Apr 9, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P19/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds comprising a linear .beta.1.fwdarw.6 glucan esterified by caproic acid, the number of D-glucose residues being from 7 to 40 and the number of caproic acid residues being from 2 to 30, may be be obtained by fermentation of a microorganism of the genus Aureobasidium. These compounds are designated HS-142-1. Preferred microorganism is Aureobasidium pullulans var. melanigenum KAC-2383 (FERM-BP 2407). The compounds of the present invention exhibit excellent antagonistic activity to ANP and are capable of inhibiting the bonding of ANP to ANP receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.