1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene biosynthesis
US5132319A · kind A · utility
13Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 28, 1991 |
| Grant date | Jul 21, 1992 |
| Priority date | — |
| Expiry date | Mar 28, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.