Patent · US Expired

Dideoxynucleoside-5'-phosphonoformic acid compounds

US5132414A · kind A · utility

3Cited by
2References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 10, 1990
Grant dateJul 21, 1992
Priority date
Expiry dateMay 10, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/20
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds having the structure ##STR1## in which R is alkyl, aryl, or aralkyl, A is hydrogen or a water-soluble cation, B is hydrogen, fluorine, or azido, the bond is saturated when B is fluorine or azido and is saturated or unsaturated when B is hydrogen, and D is a purine or pyrimidine base are effective inhibitors of retrovirus replication.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.