Method for conducting organic reactions using guanidinium salt as phase transfer catalyst
US5132423A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 13, 1991 |
| Grant date | Jul 21, 1992 |
| Priority date | — |
| Expiry date | Mar 13, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/215
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Reactions between a solid polar and a non-polar compound, especially nucleophilic aromatic substitution reactions between an alkali metal salt of a hydroxyaromatic compound or thio analog thereof and an activated halo- or nitro-substituted aromatic compound, are conducted in a non-polar organic solvent such as toluene or xylene, in the presence of a hexaalkylguanidinium or .alpha.,.omega.-bis(pentaalkylguanidinium)alkane salt, or a corresponding heterocyclic salt, as a phase transfer catalyst. The method is particularly useful for the preparation of bisimides from bisphenol A or 4,4'-biphenol salts and 4-nitro- or 4-halophthalimides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.