Process for preparing a neutralized oxidized cellulose product and its method of use
US5134229A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 13, 1990 |
| Grant date | Jul 28, 1992 |
| Priority date | — |
| Expiry date | Dec 13, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S602/90
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Oxidized cellulose material is neutralized, by contacting an acidic oxidized cellulose material with a water and alcohol solution of a basic salt of a weak organic acid, e.g. sodium acetate, to elevate the pH of the cellulosic material to between 5 and 8. The resulting neutralized product is storage stable and has therapeutic applications, including hemostasis and adhesion prevention. Furthermore, the neutralized product may be impregnated with acid-sensitive hemostatic agents, such as thrombin, to enhance its hemostatic properties, or with acid-sensitive adhesion-preventive agents, such as t-PA, to enhace its adhesion-prevention properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.