Method to preselect the sex of offspring
US5135759A · kind A · utility
183Cited by
2References
26Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 26, 1991 |
| Grant date | Aug 4, 1992 |
| Priority date | — |
| Expiry date | Apr 26, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Intact X and Y chromosome-bearing sperm populations of rabbits and swine were separated according to DNA content using a flow cytometer/cell sorter. Sperm viability was maintained by special staining techniques and by sorting and collecting the sperm in nutrient media. The sorted sperm were surgically inseminated into the uteri of rabbits or swine. Of the offspring born from does inseminated with the sorted population of X-bearing sperm, 94% were females. Of offspring born from does inseminated with sorted Y-bearing sperm from the same ejaculate, 81% were males.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.