Piezoelectric cell growth biosensing method using polymer-metabolic product complex interactions
US5135852A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 25, 1989 |
| Grant date | Aug 4, 1992 |
| Priority date | — |
| Expiry date | Jul 25, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/908
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a piezoelectric biosensor device and also to a method and a system utilizing a piezoelectric biosensor device for detecting metabolic growth requirements, antibiotic responses, and the specific bacterial products of microorganisms. When a microorganism is grown in an appropriate nutrient medium containing a metabolic product responsive polymer, metabolic products of the organism acidify the medium and precipitate a polymer metabolic product complex which deposits or accumulates on the surface of a piezoelectric biosensor device. The mass change on the surface of the device resulting from this deposit produces a change in the resonant frequency of the piezoelectric biosensor device which can be used to determine the growth and type of microorganism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.