Method and a pharmaceutical composition for the inhibition of angiogenesis
US5135919A · kind A · utility
128Cited by
4References
13Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 25, 1988 |
| Grant date | Aug 4, 1992 |
| Priority date | — |
| Expiry date | Mar 25, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/802
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fumagillin and its salts have an angiogenesis inhibiting activity and are useful for prophylaxis and treatment of diseases induced by abnormally stimulated neovascularization. The invention also provides certain pharmaceutical compositions comprising fumagillin or its salt, and an agent which potentiates angiogenesis inhibition such as heparin and sulfated cyclodextrins such as beta-cyclodextrin tetradecasulfate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.