Method of fractionating plasma proteins
US5138034A · kind A · utility
28Cited by
2References
20Claims
0Family size
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Key dates
| Filing date | Jun 14, 1990 |
| Grant date | Aug 11, 1992 |
| Priority date | — |
| Expiry date | Jun 14, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/22
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of fractionating plasma protein which comprises treating a plasma protein-containing material in the following sequence of steps, provided that steps (ii) through (v) may be performed in an optional order: (i) freeze-thaw treatment, (ii) treatment at 5 to 10% ethanol concentration, (iii) treatment with an anion exchanger, (iv) affinity chromatography with immobilized lysine, (v) affinity chromatography with immobilized heparin, (vi) treatment at 18 to 30% ethanol concentration, (vii) treatment at 35 to 45% ethanol concentration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.