Dot matrix membrane cell expansion
US5139946A · kind A · utility
47Cited by
19References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 1991 |
| Grant date | Aug 18, 1992 |
| Priority date | — |
| Expiry date | Jul 9, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/818
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
There is disclosed a perfusable cell culture device capable of expansion and maintenance of biological cells, including mammalian, microbial, plant and insect cells in culture. The device comprises an upper and lower polymeric film layer and a gas and liquid permeable flow divider membrane. The flow divider membrane is affixed between the upper and lower polymeric layers and to the lower polymeric layer in a manner providing channels for fluid distribution of culture medium which is perfused at a controlled rate, uniformly across the flow divider membrane and to a bed of cells dispersed on the flow divider membrane.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.