Antibacterial 5-alkylquinolonecarboxylic acids

US5140033A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Michael Schriewer · Odenthal, DE
• Klaus Grohe · Odenthal, DE
• Andreas Krebs · Odenthal, DE
• Uwe Petersen · Leverkusen, DE
• Thomas Schenke · Odenthal, DE
• Ingo Haller · Wuppertal, DE
• Karl G. Metzger · Wuppertal, DE
• Rainer Endermann · Wuppertal, DE
• Hans-Joachim Zeiler · Velbert, DE

Key dates

• Filing date: Oct 1, 1990
• Grant date: Aug 18, 1992
• Expiry date: Oct 1, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Antibacterial 5-alkylquinolonecarboxylic acids of the formula ##STR1## in which R.sup.3 is C.sub.1 -C.sub.4 -alkyl, PA1 R.sup.1 is optionally substituted alkyl or cycloalkyl, alkenyl, alkoxy, amino or alkylamino or optionally substituted phenyl, PA1 R.sup.2 is hydrogen or optionally substituted alkyl, PA1 R.sup.4 is a nitrogen-containing heterocyclic radical, and PA1 A is hydrogen, halogen, methyl, cyano or nitro, or forms a bridge with R.sup.1. and hydrates and salts thereof.