Process for obtaining genistin malonate and daidzin malonate
US5141746A · kind A · utility
73Cited by
6References
19Claims
0Family size
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Key dates
| Filing date | Oct 16, 1990 |
| Grant date | Aug 25, 1992 |
| Priority date | — |
| Expiry date | Oct 16, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/522
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Genistin and daidzin malonates are obtained by extracting ground soya bean with methanol or ethanol to obtain an extract. The extract is buffered to a pH of 6 to 9 and then extracted with a water-immiscible solvent. The aqueous phase is recovered, acidified to a pH of 2 to 5.4, and then extracted with a water-immiscible solvent. The organic phase is recovered, neutralized to a pH of 6.8 to 7.2, and the malonates are separated therefrom.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.