Preparation of acylated sucrose derivatives
US5141860A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1989 |
| Grant date | Aug 25, 1992 |
| Priority date | — |
| Expiry date | Sep 26, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H13/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Sucrose derivatives partially acylated in each ring can be obtained by treating a fully or partially acylated sucrose derivative with an enzyme having sucrose esterase activity capable of removing at least one acyl group from each ring, generally comprising or being a component of a lipase, esterase, amylase, .alpha.-galactosidase or protease preparation, the enzyme treatment being effected in an aqueous system. Sucralose can be obtained by using this method to obtain a sucrose 2,3,6,3',4'-penta ester which can then be chlorinated and de-esterfied. Some of the penta acetates, tetraacetates and mixed acetates/butyrates are new compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.