Erythromycin derivatives
US5141926A · kind A · utility
37Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 18, 1990 |
| Grant date | Aug 25, 1992 |
| Priority date | — |
| Expiry date | Apr 18, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/882
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel 6-deoxyerythromycin derivatives are disclosed, as are methods for their preparation and use as antiinfective agents. The compounds of the invention include 6-deoxyerythromycins and 6-deoxy-15-norerythromycins which are represented by the structural formula ##STR1## in which R.sub.1 is selected from OH and H, and R.sub.2 and R.sub.3 are independently selected from H and CH.sub.3, as well as the pharmaceutically acceptable salts and esters of the above compounds. Additionally disclosed are genetically modified microorganisms which produce the compounds of the invention and means for the preparation of those microorganisms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.