Cationized carriers for immunogen production
US5142027A · kind A · utility
3Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 21, 1990 |
| Grant date | Aug 25, 1992 |
| Priority date | — |
| Expiry date | Nov 21, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6081
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A conjugate of a protein carrier and an antigen is disclosed. The carrier protein is cationized and the conjugate has enhanced immunogenic properties over those of the antigen alone. Cationization can be accomplished by derivatization of native carboxyl groups on the protein with an aklyl diamine, e.g. ethylene diamine, resulting in the formation of side chain aminoalkylamide groups, e.g. aminoethylamide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.