Cephalosporin intermediates
US5142041A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 22, 1991 |
| Grant date | Aug 25, 1992 |
| Priority date | — |
| Expiry date | Mar 22, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides certain novel cephalosporin derivatives represented by following formula(I), which are especially useful as intermediates for the preparation of cephalosporin compounds possessed with potent and broad antibacterial activities. ##STR1## wherein: R.sup.1 is a C.sub.1-4 alkyl, C.sub.3-4 alkenyl, C.sub.3-4 cycloalkyl, amino optionally substituted with a C.sub.1-4 alkyl radical, or phenyl group optionally substituted on its 2-, 4-and/or 6-position with a halogen, C.sub.1-4 alkyl, C.sub.1-3 alkoxy or hydroxy radical; PA0 R.sup.2 is hydrogen or a C.sub.1-4 alkyl group; and PA0 n is either 0 or 1. The invention also relates to processes for preparing these intermediates and their pharmacologically active cephalosporin antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.