Techniques for enhancing the permeability of ions through membranes
US5143588A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 2, 1990 |
| Grant date | Sep 1, 1992 |
| Priority date | — |
| Expiry date | Aug 2, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2/02
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method is provided for enhancing the transport of a selected ion having a predetermined charge-to-mass ratio through a biomolecular membrane located in a space subjected to a local magnetic field. The space defines at least one reference path passing through the membrane in opposite first and second directions. The method includes the steps of creating a magnetic field which, when combined with the local magnetic field, produces a magnetic field having a flux density with at least one component representable by a component vector having a direction extending in the first direction along the path. This component of the magnetic field has a magnitude that fluctuates at a predetermined rate to produce a nonzero average value. A predetermined relationship between the ratio of the selected rate to the nonzero average value and the charge-to-mass ratio of the predetermined ion is thereby created. The predetermined relationship is a function of the cyclotron resonance frequency of the ion. The present invention also provides an apparatus for enhancing the transport of a selected ion having a predetermined charge-to-mass ratio through a biomolecular membrane. The apparatus includes field…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.