Patent · US Expired

Method and apparatus for preparing cells for examination

US5143627A · kind A · utility

59Cited by
14References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 9, 1990
Grant dateSep 1, 1992
Priority date
Expiry dateJul 9, 2010

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/2575
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An apparatus and method provide automated collection and transfer of particles from a liquid suspension to a glass slide for visual examination. A solution which contains particles, for example cells, is drawn through a filter element so that particles too large to pass through the filter element collect against a first surface of the filter element. A transfer fluid, such as alcohol, is applied from a second surface of the filter element to the first surface, to transfer cells from the filter element to a glass slide positioned adjacent the filter element. An alternative transfer mechanism applies a selected pneumatic signal to the filter element for transferring collected cells to the viewing slide. The apparatus includes a device for dispersing the liquid suspension of particles prior to the collection process and particles collect against the filter element with a spatial distribution advantageous for visual examination. The transfer operation maintains this spatial distribution. The cell-dispersing device and the filter element are on a common structure, for unitary movement, and which is readily disposable and replaceable for each sample of particles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.